Generation of a Biomimetic Substitute of the Corneal Limbus Using Decellularized Scaffolds

• Main Authors: David Sánchez-Porras (Author), Manuel Caro-Magdaleno (Author), Carmen González-Gallardo (Author), Óscar Darío García-García (Author), Ingrid Garzón (Author), Víctor Carriel (Author), Fernando Campos (Author), Miguel Alaminos (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Patients with severe limbal damage and limbal stem cell deficiency are a therapeutic challenge. We evaluated four decellularization protocols applied to the full-thickness and half-thickness porcine limbus, and we used two cell types to recellularize the decellularized limbi. The results demonstrate...