Increased activated memory B-cells in the peripheral blood of patients with erythema nodosum leprosum reactions.

• Main Authors: Edessa Negera (Author), Stephen L Walker (Author), Yonas Bekele (Author), Hazel M Dockrell (Author), Diana N Lockwood (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

B-cells, in addition to antibody secretion, have emerged increasingly as effector and immunoregulatory cells in several chronic inflammatory diseases. Although Erythema Nodosum Leprosum (ENL) is an inflammatory complication of leprosy, the role of B- cell subsets has never been studied in this patie...