Ranolazine Attenuates the Enhanced Reverse Na+-Ca2+ Exchange Current via Inhibiting Hypoxia-Increased Late Sodium Current in Ventricular Myocytes

Ranolazine (RAN), a novel antianginal agent, inhibits the increased late sodium current (INa.L) under many pathological conditions. In this study, the whole-cell patch-clamp technique was used to explore the effects of RAN on INa.L and reverse Na+/Ca2+ exchange current (INCX) in rabbit ventricular m...

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Main Authors: Xiao-Jing Wang (Author), Lei-Lei Wang (Author), Chen Fu (Author), Pei-Hua Zhang (Author), Ying Wu (Author), Ji-Hua Ma (Author)
Format: Book
Published: Elsevier, 2014-01-01T00:00:00Z.
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