Prediction of hERG inhibition of drug discovery compounds using biomimetic HPLC measurements

The major causes of failure of drug discovery compounds in clinics are the lack of efficacy and toxicity. To reduce late-stage failures in the drug discovery process, it is essential to estimate early the probability of adverse effects and potential toxicity. Cardiotoxicity is one of the most often...

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Main Authors: Chrysanthos Stergiopoulos (Author), Fotios Tsopelas (Author), Klara Valko (Author)
Format: Book
Published: International Association of Physical Chemists (IAPC), 2021-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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