Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular repair responses and angiogenesis

• Main Authors: Yihong Chen (Author), Chrysostomi Gialeli (Author), Junyan Shen (Author), Pontus Dunér (Author), Björn Walse (Author), Annette Duelli (Author), Rhawnie Caing-Carlsson (Author), Anna M. Blom (Author), John R. Zibert (Author), Anna Hultgårdh Nilsson (Author), Jan Alenfall (Author), Chun Liang (Author), Jan Nilsson (Author)
• Format: Book
• Published: Elsevier, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The osteopontin-derived peptide FOL-005 stimulates hair growth. Using ligand-receptor glyco-capture technology we identified neuropilin-1 (NRP-1), a known co-receptor for vascular endothelial growth factor (VEGF) receptors, as the most probable receptor for FOL-005 and the more stable analogue FOL-0...