Curcumin represses NLRP3 inflammasome activation via TLR4/MyD88/NF-κB and P2X7R signaling in PMA-induced macrophages

• Main Authors: Fanqi Kong (Author), Bozhi Ye (Author), Jiatian Cao (Author), Xueli Cai (Author), Lu Lin (Author), Shanjun Huang (Author), Weijian Huang (Author), Zhouqing Huang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractAims: In the NOD-like receptor (NLR) family, the pyrin domain containing 3 (NLRP3) inflammasome is closely related to the progression of atherosclerosis. This study aimed to assess the effects of curcumin on NLRP3 inflammasome in phorbol 12-myristate 13-acetate (PMA)-induced macrophages and...