SPECT Imaging of SST2-Expressing Tumors with ^99mTc-Based Somatostatin Receptor Antagonists: The Role of Tetraamine, HYNIC, and Spacers

• Main Authors: Raghuvir Haridas Gaonkar (Author), Fabius Wiesmann (Author), Luigi Del Pozzo (Author), Lisa McDougall (Author), Sandra Zanger (Author), Renata Mikołajczak (Author), Rosalba Mansi (Author), Melpomeni Fani (Author)
• Format: Book
• Published: MDPI AG, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

[^99mTc]Tc-HYNIC-TOC is the most widely used ^99mTc-labeled somatostatin receptor (SST) agonist for the SPECT imaging of SST-expressing tumors, such as neuroendocrine tumors. Recently, radiolabeled SST antagonists have shown improved diagnostic efficacy ov...