Gene-gene interaction and association of Wnt/Β-catenin signalling pathway gene polymorphisms with ankylosing spondylitis susceptibility in the Chinese Han population

• Main Authors: Rui Liu (Author), Xu Zhang (Author), Guangming Jiang (Author), Yubo Ma (Author), Jiajia Yang (Author), Meng Wu (Author), Renfang Han (Author), Mengya Chen (Author), Yaping Yuan (Author), Xingxing Hu (Author), Meijuan Pan (Author), Shengqian Xu (Author), Jianhua Xu (Author), Zongwen Shuai (Author), Yanfeng Zou (Author), Guixia Pan (Author), Faming Pan (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: To explore the genetic interaction between Wnt/β-catenin signalling pathway genes and ankylosing spondylitis (AS) in the Chinese population. Methods: Six single-nucleotide polymorphisms (SNPs) in DKK1, LRP5, LRP6, and SOST genes were genotyped in 673 AS patients and 687 healthy controls...