Insight into the Formation of Glimepiride Nanocrystals by Wet Media Milling

• Main Authors: Djordje Medarević (Author), Svetlana Ibrić (Author), Elisavet Vardaka (Author), Miodrag Mitrić (Author), Ioannis Nikolakakis (Author), Kyriakos Kachrimanis (Author)
• Format: Book
• Published: MDPI AG, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nanocrystal formation for the dissolution enhancement of glimepiride was attempted by wet media milling. Different stabilizers were tested and the obtained nanosuspensions were solidified by spray drying in presence of mannitol, and characterized regarding their redispersibility by dynamic light sca...