Cytoprotective Effects of Water Soluble Dihydropyrimidinthione Derivative Against UV-B Induced Human Corneal Epithelial Cell Photodamage

• Váldodahkkit: Enming Du (Dahkki), Guojuan Pu (Dahkki), Siyu He (Dahkki), Fangyuan Qin (Dahkki), Yange Wang (Dahkki), Gang Wang (Dahkki), Zongming Song (Dahkki), Junjie Zhang (Dahkki), Ye Tao (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Excessive UV-B exposure is well known to be a risk factor for corneal phototoxicity including direct DNA damage and disturbances in the antioxidant balance. Here, we showed a successful synthesis of a water-soluble and biocompatible small molecule DHPM 1 with dihydropyrimidinthione skeleton, which c...