Cytoprotective Effects of Water Soluble Dihydropyrimidinthione Derivative Against UV-B Induced Human Corneal Epithelial Cell Photodamage

• मुख्य लेखकों: Enming Du (लेखक), Guojuan Pu (लेखक), Siyu He (लेखक), Fangyuan Qin (लेखक), Yange Wang (लेखक), Gang Wang (लेखक), Zongming Song (लेखक), Junjie Zhang (लेखक), Ye Tao (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Excessive UV-B exposure is well known to be a risk factor for corneal phototoxicity including direct DNA damage and disturbances in the antioxidant balance. Here, we showed a successful synthesis of a water-soluble and biocompatible small molecule DHPM 1 with dihydropyrimidinthione skeleton, which c...