NAb-seq: an accurate, rapid, and cost-effective method for antibody long-read sequencing in hybridoma cell lines and single B cells

• Главные авторы: Hema Preethi Subas Satish (Автор), Kathleen Zeglinski (Автор), Rachel T. Uren (Автор), Stephen L. Nutt (Автор), Matthew E. Ritchie (Автор), Quentin Gouil (Автор), Ruth M. Kluck (Автор)
• Формат: ‌
• Опубликовано: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Предметы: article
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Despite their common use in research, monoclonal antibodies are currently not systematically sequenced. This can lead to issues with reproducibility and the occasional loss of antibodies with loss of cell lines. Hybridoma cell lines have been the primary means of generating monoclonal antibodies fro...