Antimalarial and antioxidant activities of novel artesunate-ellagic acid hybrid compound in vitro and in vivo

• Main Authors: Ahmed A. Ishola (Author), Joseph O. Adebayo (Author), Isabela P. Ceravolo (Author), Habibu Tijjani (Author), Edson S. Bento (Author), Henrique F. Goulart (Author), Alessandre C. Crispim (Author), Elizabeth A. Balogun (Author), Antonio E. G. Santana (Author), Antoniana U. Krettli (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Emergence of drug resistant strains of Plasmodium species has necessitated the search for novel antimalarials with unique mechanisms of action. Synthesis of hybrid compounds has been one approach to tackling this challenge. In this study, the synthesis of artesunate-ellagic acid hybrid...