Downregulation of TLR4 by miR-181a Provides Negative Feedback Regulation to Lipopolysaccharide-Induced Inflammation

• Main Authors: Kangfeng Jiang (Author), Shuai Guo (Author), Tao Zhang (Author), Yaping Yang (Author), Gan Zhao (Author), Aftab Shaukat (Author), Haichong Wu (Author), Ganzhen Deng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute lung injury (ALI) is a progressive clinical disease with a high mortality rate, and characterized by an excessive uncontrolled inflammatory response. MicroRNAs (miRNAs) play a critical role in various human inflammatory diseases, and have been recognized as important regulators of inflammation...