Activation of Toll-Like Receptor 3 Induces Interleukin-1 Receptor Antagonist Expression by Activating the Interferon Regulatory Factor 3

• Glavni autori: Yang Liu (Autor), Chun-Fen Mo (Autor), Xing-Yan Luo (Autor), Hua Li (Autor), Hui-Jie Guo (Autor), Hai Sun (Autor), Song Hu (Autor), Li-Mei Li (Autor), Yan-Tang Wang (Autor), Shu-Xia Yang (Autor), Shan Chang (Autor), Qiang Zou (Autor)
• Format: Knjiga
• Izdano: Karger Publishers, 2019-12-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Toll-like receptor 3 (TLR3) is a sensor of endogenous cell necrosis during the process of acute inflammation. Interleukin (IL)-1 receptor antagonist (IL-1Ra) is an anti-inflammatory cytokine and can negatively regulate the pathogenesis of inflammation. However, whether and how activation of TLR3 can...