Striatum hyperactivity triggers relapse to morphine and methamphetamine (polydrug) dependence in mice

• Main Authors: Nur Syafinaz Wasli (Author), Irna Elina Ridzwan (Author), Marwan Saad Azzubaidi (Author), Abdul Razak Kasmuri (Author), Qamar Uddin Ahmed (Author), Long Chiau Ming (Author), Nornisah Mohamed (Author), Syed Mohd Syahmi Syd Mohmad Faudzi (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: κ-opioid receptor (KOPr) system has been linked to relapse to many substances, especially opioids. Positive responses were recently reported in morphine and methamphetamine (polydrug)-dependent mice treated with buprenorphine and naltrexone, a functional κ antagonist. Objectives: This...