Xanthohumol alleviates oxidative stress and impaired autophagy in experimental severe acute pancreatitis through inhibition of AKT/mTOR

• Main Authors: Yaru Huangfu (Author), Xiuxian Yu (Author), Chengyu Wan (Author), Yuda Zhu (Author), Zeliang Wei (Author), Fan Li (Author), Yilan Wang (Author), Kun Zhang (Author), Shiyi Li (Author), Yuman Dong (Author), Yangying Li (Author), Hai Niu (Author), Guang Xin (Author), Wen Huang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Severe acute pancreatitis (SAP) is a lethal gastrointestinal disorder, yet no specific and effective treatment is available. Its pathogenesis involves inflammatory cascade, oxidative stress, and autophagy dysfunction. Xanthohumol (Xn) displays various medicinal properties,including anti-inflammation...