Neuroprotective Effects of Nano-Curcumin against Cypermethrin Associated Oxidative Stress and Up-Regulation of Apoptotic and Inflammatory Gene Expression in Rat Brains

• Main Authors: Mohammad Ashafaq (Author), Sohail Hussain (Author), Saeed Alshahrani (Author), Rahimullah Siddiqui (Author), Mohammad Intakhab Alam (Author), Manal Mohamed Elhassan Taha (Author), Yosif Almoshari (Author), Saad S. Alqahtani (Author), Abdulmajeed M. Jali (Author), Hashim M. Aljohani (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cypermethrin (CPM) is the most toxic synthetic pyrethroid that has established neurotoxicity through oxidative stress and neurochemical agitation in experimental rats. The toxic effects are supposed to be mediated by modifying the sodium channels, reducing Na-K ATPase, acetylcholine esterase (AchE),...