Echinacoside exerts antidepressant-like effects through enhancing BDNF-CREB pathway and inhibiting neuroinflammation via regulating microglia M1/M2 polarization and JAK1/STAT3 pathway

The present study was performed to investigate the antidepressant effect of echinacoside (ECH) using chronic unpredictable mild stress (CUMS) induced depression mice and lipopolysaccharide (LPS)-stimulated N9 microglial cells. CUMS treatment was performed on C57BL/6 mice for 28 days, followed by gav...

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Main Authors: Renrui Lu (Author), Li Zhang (Author), Huihui Wang (Author), Meng Li (Author), Weisheng Feng (Author), Xiaoke Zheng (Author)
Format: Book
Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
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