Brucella abortus RNA does not polarize macrophages to a particular profile but interferes with M1 polarization.

• Main Authors: Agustina Serafino (Author), José L Marin Franco (Author), Mariano Maio (Author), Aldana Trotta (Author), Melanie Genoula (Author), Luis A Castillo (Author), Federico Birnberg Weiss (Author), José R Pittaluga (Author), Luciana Balboa (Author), Paula Barrionuevo (Author), M Ayelén Milillo (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Monocytes and macrophages play a central role in chronic brucellosis. Brucella abortus (Ba) is an intracellular pathogen that survives inside these cells. On the other hand, macrophages could be differentiated into classical (M1), alternative (M2) or other less-identified profiles. We have previousl...