Case Report: Therapeutic Drug Monitoring of Polymyxin B During Continuous Renal Replacement Therapy in Two Pediatric Patients: Do Not Underestimate Extracorporeal Clearance

• Main Authors: Caifang Xu (Author), Xiaofen Liu (Author), Yun Cui (Author), Xiaolan Huang (Author), Yu Wang (Author), Yaxin Fan (Author), Hailan Wu (Author), Xin Li (Author), Beining Guo (Author), Jing Zhang (Author), Yucai Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Polymyxin B has become the last choice for patient with carbapenem-resistant bacterial infection. However, the optimal dosing of polymyxin B in critically ill children receiving continuous renal replacement therapy (CRRT) remains unclear.Case Presentation: Two cases of critically ill ped...