Circulating exosomal microRNAs as potential biomarkers of hepatic injury and inflammation in a murine model of glycogen storage disease type 1a

• Main Authors: Roberta Resaz (Author), Davide Cangelosi (Author), Martina Morini (Author), Daniela Segalerba (Author), Luca Mastracci (Author), Federica Grillo (Author), Maria Carla Bosco (Author), Cristina Bottino (Author), Irma Colombo (Author), Alessandra Eva (Author)
• Format: Book
• Published: The Company of Biologists, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Most patients affected by glycogen storage disease type 1a (GSD1a), an inherited metabolic disorder caused by mutations in the enzyme glucose-6-phosphatase-α (G6Pase-α), develop renal and liver complications, including the development of hepatocellular adenoma/carcinoma. The purpose of this study wa...