LKB1 deficiency-induced metabolic reprogramming in tumorigenesis and non-neoplastic diseases
Background: Live kinase B1 (LKB1) is a tumor suppressor that is mutated in Peutz-Jeghers syndrome (PJS) and a variety of cancers. Lkb1 encodes serine-threonine kinase (STK) 11 that activates AMP-activated protein kinase (AMPK) and its 13 superfamily members, regulating multiple biological processes,...
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| Main Authors: | , , , , , |
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| Format: | Book |
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Elsevier,
2021-02-01T00:00:00Z.
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