Future Trends in the Pharmacogenomics of Brain Disorders and Dementia: Influence of APOE and CYP2D6 Variants

• Main Authors: Antón Álvarez (Author), Verónica Couceiro (Author), Susana Rodríguez (Author), Ángela Casas (Author), Margarita Alcaraz (Author), Laura Nebril (Author), Iván Tellado (Author), Iván Carrera (Author), Lola Corzo (Author), Valter Lombardi (Author), Adam McKay (Author), Juan C. Carril (Author), Ramón Cacabelos (Author), Rocío Martínez-Bouza (Author), Lucía Fernández-Novoa (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2010-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

About 80% of functional genes in the human genome are expressed in the brain and over 1,200 different genes have been associated with the pathogenesis of CNS disorders and dementia. Pharmacogenetic studies of psychotropic drug response have focused on determining the relationship between variations...