Novel Bacterial Topoisomerase inhibitors (NBTIs) - A comprehensive review

• मुख्य लेखकों: Jigar Desai (लेखक), Sachchidanand S (लेखक), Sanjay Kumar (लेखक), Rajiv Sharma (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2021-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Bacterial DNA gyrase and topoisomerase IV inhibition has emerged as a promising strategy for the cure of infections caused by antibiotic-resistant bacteria. Small molecule antibacterials inhibiting bacterial topoisomerases have been previously exploited by the successful fluoroquinolone class. The N...