Stool is a sensitive and noninvasive source of DNA for monitoring expansion in repeat expansion disease mouse models

Repeat expansion diseases are a large group of human genetic disorders caused by expansion of a specific short tandem repeat tract. Expansion in somatic cells affects age of onset and disease severity in some of these disorders. However, alleles in DNA derived from blood, a commonly used source of D...

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主要な著者: Xiaonan Zhao (著者), Cassandra McHugh (著者), Sydney R. Coffey (著者), Diego Antonio Jimenez (著者), Elizabeth Adams (著者), Jeffrey B. Carroll (著者), Karen Usdin (著者)
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出版事項: The Company of Biologists, 2022-05-01T00:00:00Z.
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