In vitro and in vivo high-throughput assays for the testing of anti-Trypanosoma cruzi compounds.

In vitro and in vivo high-throughput assays for the testing of anti-Trypanosoma cruzi compounds.

The two available drugs for treatment of T. cruzi infection, nifurtimox and benznidazole (BZ), have potential toxic side effects and variable efficacy, contributing to their low rate of use. With scant economic resources available for antiparasitic drug discovery and development, inexpensive, high-t...

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Main Authors: Adriana M C Canavaci (Author), Juan M Bustamante (Author), Angel M Padilla (Author), Cecilia M Perez Brandan (Author), Laura J Simpson (Author), Dan Xu (Author), Courtney L Boehlke (Author), Rick L Tarleton (Author)
Format: Book
Published: Public Library of Science (PLoS), 2010-07-01T00:00:00Z.
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3rd Floor Main Library

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