Generation and Application of a Reporter Cell Line for the Quantitative Screen of Extracellular Vesicle Release

• Main Authors: Jonathan Shpigelman (Author), Fitzgerald S. Lao (Author), Shiyin Yao (Author), Chenyang Li (Author), Tetsuya Saito (Author), Fumi Sato-Kaneko (Author), John P. Nolan (Author), Nikunj M. Shukla (Author), Minya Pu (Author), Karen Messer (Author), Howard B. Cottam (Author), Dennis A. Carson (Author), Maripat Corr (Author), Tomoko Hayashi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Extracellular vesicles (EVs) are identified as mediators of intercellular communication and cellular regulation. In the immune system, EVs play a role in antigen presentation as a part of cellular communication. To enable drug discovery and characterization of compounds that affect EV biogenesis, fu...