Crosstalk between TM4SF5 and GLUT8 regulates fructose metabolism in hepatic steatosis

• Main Authors: Hyejin Lee (Author), Eunmi Kim (Author), Eun-Ae Shin (Author), Jong Cheol Shon (Author), Hyunseung Sun (Author), Ji Eon Kim (Author), Jae Woo Jung (Author), Haesong Lee (Author), Yangie Pinanga (Author), Dae-Geun Song (Author), Kwang-Hyeon Liu (Author), Jung Weon Lee (Author)
• Format: Book
• Published: Elsevier, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Transmembrane 4 L six family member 5 (TM4SF5) is likely involved in non-alcoholic steatohepatitis, although its roles and cross-talks with glucose/fructose transporters in phenotypes derived from high-carbohydrate diets remain unexplored. Here, we investigated the modulation of hepatic f...