The HER-2 as a Target Gene of Curcumin to Protect Hepatocytes Against the Arsenic-induced Carcinoma in Mice

• Những tác giả chính: Mahdi Ahadi (Tác giả), Vahid Naseh (Tác giả), Masoud Salehipour (Tác giả)
• Định dạng: Sách
• Được phát hành: Iranian Society of Pathology, 2017-04-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Background & objective: The HER-2 gene is an important on co protein overexpressed in many types of cancers. The current study hypothesized that curcumin downregulates HER-2 and inhibits the signal transduction pathway of PI3K/Akt, MAPK, and activation of NFκB, which could be useful to treat ove...