Anilino-1,4-naphthoquinones as potent mushroom tyrosinase inhibitors: in vitro and in silico studies

• Main Authors: Sahachai Sabuakham (Author), Sutita Nasoontorn (Author), Napat Kongtaworn (Author), Thanyada Rungrotmongkol (Author), Atit Silsirivanit (Author), Ratchanok Pingaew (Author), Panupong Mahalapbutr (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tyrosinase, a pivotal enzyme in melanin synthesis, is a primary target for the development of depigmenting agents. In this work, in vitro and in silico techniques were employed to identify novel tyrosinase inhibitors from a set of 12 anilino-1,4-naphthoquinone derivatives. Results from the mushroom...