Anilino-1,4-naphthoquinones as potent mushroom tyrosinase inhibitors: in vitro and in silico studies

• Hlavní autoři: Sahachai Sabuakham (Autor), Sutita Nasoontorn (Autor), Napat Kongtaworn (Autor), Thanyada Rungrotmongkol (Autor), Atit Silsirivanit (Autor), Ratchanok Pingaew (Autor), Panupong Mahalapbutr (Autor)
• Médium: Kniha
• Vydáno: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Tyrosinase, a pivotal enzyme in melanin synthesis, is a primary target for the development of depigmenting agents. In this work, in vitro and in silico techniques were employed to identify novel tyrosinase inhibitors from a set of 12 anilino-1,4-naphthoquinone derivatives. Results from the mushroom...