Immunohistochemical study of macrophages subpopulations associated with squamous cell carcinoma of the tongue, with and without metastasis

• Main Authors: Natália G. Barbosa (Author), Melka C. Sá (Author), Leão P. Pinto (Author), Roseana A. Freitas (Author)
• Format: Book
• Published: Sociedade Brasileira de Patologia Clínica, 2015-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT Introduction: Stromal cells interact with tumor cells and play an important role in cancer invasion and metastasis. Tumor-associated macrophages (TAMs) can exhibit M1 phenotype, important immune effector cells, or M2 phenotype, able to suppress the function of M1 macrophages and influence a...