Hypertension related toxicity of chloroquine explains its failure against COVID-19: Based on rat model

• Автори: Junqi Wang (Автор), Xian Jing (Автор), Lizhong Hua (Автор), Yuling Zheng (Автор), Shiheng Hu (Автор), Jing Xiao (Автор), Dawei Guo (Автор), Wenda Wu (Автор), Hui Ji (Автор), Lin Peng (Автор), Shanxiang Jiang (Автор), Xiuge Gao (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Chloroquine was once thought to be a promising treatment for COVID-19 but it quickly failed due to its inefficiency and association with increased mortality. Further, comorbidities such as hypertension may have contributed this failure. The safety and toxicity of chloroquine at doses required for tr...