4-Aminoquinoline-Based Adamantanes as Potential Anticholinesterase Agents in Symptomatic Treatment of Alzheimer's Disease

• Main Authors: Katarina Komatović (Author), Ana Matošević (Author), Nataša Terzić-Jovanović (Author), Suzana Žunec (Author), Sandra Šegan (Author), Mario Zlatović (Author), Nikola Maraković (Author), Anita Bosak (Author), Dejan M. Opsenica (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Considering that acetylcholinesterase (AChE) inhibition is the most important mode of action expected of a potential drug used for the treatment of symptoms of Alzheimer's disease (AD), our previous pilot study of 4-aminoquinolines as potential human cholinesterase inhibitors was extended to tw...