Bioequivalence of Oral Drug Products in the Healthy and Special Populations: Assessment and Prediction Using a Newly Developed In Vitro System "BE Checker"

• Main Authors: Takato Masada (Author), Toshihide Takagi (Author), Keiko Minami (Author), Makoto Kataoka (Author), Ken-ichi Izutsu (Author), Kazuki Matsui (Author), Shinji Yamashita (Author)
• Format: Book
• Published: MDPI AG, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In order to assess and predict the bioequivalence (BE) of oral drug products, a new in vitro system "BE checker" was developed, which reproduced the environmental changes in the gastrointestinal (GI) tract by changing the pH, composition, and volume of the medium in a single chamber. The d...