Alpha-Ketoglutarate and 5-HMF: A Potential Anti-Tumoral Combination against Leukemia Cells

• المؤلفون الرئيسيون: Joachim Greilberger (مؤلف), Ralf Herwig (مؤلف), Michaela Greilberger (مؤلف), Philipp Stiegler (مؤلف), Reinhold Wintersteiger (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2021-11-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

We have recently shown that a combined solution containing alpha-ketoglutarate (aKG) and 5-hydroxymethyl-furfural (5-HMF) might have anti-tumoral potential due to its antioxidative activities. The question arises if these substances have caspase-3- and apoptosis-activating effects on the cell prolif...