Simultaneous determination of four Sudan dyes in rat blood by UFLCâMS/MS and its application to a pharmacokinetic study in rats

• Main Authors: Hao Zhu (Author), Yijun Chen (Author), Changshun Huang (Author), Yangyang Han (Author), Yiwei Zhang (Author), Shucan Xie (Author), Xiaohong Chen (Author), Micong Jin (Author)
• Format: Book
• Published: Elsevier, 2015-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A rapid and sensitive method based on ultrafast liquid chromatographyâtandem mass spectrometry was developed and validated for simultaneous determination of Sudan I, Sudan II, Sudan III, and Sudan IV levels in rat whole blood. Cleanert C18 mixed-mode polymeric sorbent was used for effective solid-ph...