Ameliorative effects of pirfenidone in chronic kidney disease

• Main Authors: Samad Ghodrati (Author), Yeganeh Ragati Haghi (Author), Jyoti Baharani (Author), Akshaya Joseph (Author), Niloufar Alimohammadi (Author), Farzad Koosha (Author), Leila Mostafavi (Author), Aiyoub Pezeshgi (Author)
• Format: Book
• Published: Society of Diabetic Nephropathy Prevention, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Renal fibrosis is the hallmark of advanced chronic kidney disease (CKD), which is characterized by excessive accumulation of extracellular matrix (ECM) proteins and plays a central role in the pathogenesis and progression of CKD to end-stage renal disease (ESRD). The molecular and cellular substance...