A Novel Ferroptosis Inhibitor UAMC-3203, a Potential Treatment for Corneal Epithelial Wound

• Main Authors: Anusha Balla (Author), Bao Tran (Author), Annika Valtari (Author), Philipp Steven (Author), Camilla Scarpellini (Author), Koen Augustyns (Author), Arto Urtti (Author), Kati-Sisko Vellonen (Author), Marika Ruponen (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Corneal wound, associated with pain, impaired vision, and even blindness, is the most common ocular injury. In this study, we investigated the effect of a novel ferroptosis inhibitor, UAMC-3203 (10 nM-50 µM), in corneal epithelial wound healing in vitro in human corneal epithelial (HCE) cells and ex...