Indoxyl Sulfate Induces Mesangial Cell Proliferation via the Induction of COX-2

• Main Authors: Shuzhen Li (Author), Sijie Cheng (Author), Zhenzhen Sun (Author), Harr-keshauve Mungun (Author), Wei Gong (Author), Jing Yu (Author), Weiwei Xia (Author), Yue Zhang (Author), Songming Huang (Author), Aihua Zhang (Author), Zhanjun Jia (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Indoxyl sulfate (IS) is one of important uremic toxins and is markedly accumulated in the circulation of end stage renal disease (ESRD) patients, which might contribute to the damage of residual nephrons and progressive loss of residual renal function (RRF). Thus this study was undertaken to investi...