Diminishing returns, increasing risks: Impact of antibiotic duration of therapy on respiratory bacterial isolates in hospitalized patients during the coronavirus disease 2019 (COVID-19) pandemic

• Main Authors: Catherine Li (Author), Ryan W. Chapin (Author), Nicholas J. Mercuro (Author), Christina F. Yen (Author), Howard S. Gold (Author), Matthew S. L. Lee (Author), Christopher McCoy (Author)
• Format: Book
• Published: Cambridge University Press, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In 829 hospital encounters for patients with COVID-19, 73.2% included orders for antibiotics; however, only 1.8% had respiratory cultures during the first 3 hospital days isolating bacteria. Case-control analysis of 30 patients and 96 controls found that each antibiotic day increased the risk of iso...