Monitoring of inflammation using novel biosensor mouse model reveals tissue- and sex-specific responses to Western diet

• Glavni autori: Sarah Talley (Autor), Raiza Bonomo (Autor), Chaitanya Gavini (Autor), Jomana Hatahet (Autor), Emily Gornick (Autor), Tyler Cook (Autor), Byeong Jae Chun (Autor), Pete Kekenes-Huskey (Autor), Gregory Aubert (Autor), Edward Campbell (Autor), Virginie Mansuy-Aubert (Autor)
• Format: Knjiga
• Izdano: The Company of Biologists, 2022-06-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Obesity is an epidemic, and it is characterized by a state of low-grade systemic inflammation. A key component of inflammation is the activation of inflammasomes, multiprotein complexes that form in response to danger signals and that lead to activation of caspase-1. Previous studies have found that...