Knockdown of TANK-Binding Kinase 1 Enhances the Sensitivity of Hepatocellular Carcinoma Cells to Molecular-Targeted Drugs

• Main Authors: Fengxia Du (Author), Huiwei Sun (Author), Fang Sun (Author), Shiwei Yang (Author), Haidong Tan (Author), Xiaojuan Li (Author), Yantao Chai (Author), Qiyu Jiang (Author), Dongdong Han (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The protein kinase, TANK-binding kinase 1 (TBK1), not only regulates various biological processes but also functions as an important regulator of human oncogenesis. However, the detailed function and molecular mechanisms of TBK1 in hepatocellular carcinoma (HCC), especially the resistance of HCC cel...