Renoprotective Effect of Pitavastatin against TAA-Induced Renal Injury: Involvement of the miR-93/PTEN/AKT/mTOR Pathway

• Main Authors: Marawan A. Elbaset (Author), Bassim M. S. A. Mohamed (Author), Passant E. Moustafa (Author), Tuba Esatbeyoglu (Author), Sherif M. Afifi (Author), Alyaa F. Hessin (Author), Sahar S. Abdelrahman (Author), Hany M. Fayed (Author)
• Format: Book
• Published: Hindawi Limited, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This research investigated if pitavastatin (Pita) might protect rats' kidneys against thioacetamide (TAA). By altering the PTEN/AKT/mTOR pathway, pitavastatin may boost kidney antioxidant capacity and minimize oxidative damage. Statins have several benefits, including antioxidant and anti-infla...