Renoprotective Effect of Pitavastatin against TAA-Induced Renal Injury: Involvement of the miR-93/PTEN/AKT/mTOR Pathway

• Главные авторы: Marawan A. Elbaset (Автор), Bassim M. S. A. Mohamed (Автор), Passant E. Moustafa (Автор), Tuba Esatbeyoglu (Автор), Sherif M. Afifi (Автор), Alyaa F. Hessin (Автор), Sahar S. Abdelrahman (Автор), Hany M. Fayed (Автор)
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• Опубликовано: Hindawi Limited, 2024-01-01T00:00:00Z.
• Предметы: article
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This research investigated if pitavastatin (Pita) might protect rats' kidneys against thioacetamide (TAA). By altering the PTEN/AKT/mTOR pathway, pitavastatin may boost kidney antioxidant capacity and minimize oxidative damage. Statins have several benefits, including antioxidant and anti-infla...