Absence of the kinase S6k1 mimics the effect of chronic endurance exercise on glucose tolerance and muscle oxidative stress

• Main Authors: C. Binsch (Author), T. Jelenik (Author), A. Pfitzer (Author), M. Dille (Author), S. Müller-Lühlhoff (Author), S. Hartwig (Author), S. Karpinski (Author), S. Lehr (Author), D.G. Kabra (Author), A. Chadt (Author), M. Roden (Author), H. Al-Hasani (Author), T.R. Castañeda (Author)
• Format: Book
• Published: Elsevier, 2017-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Ribosomal protein S6 Kinase-1 (S6K1) has been linked to resistance exercise-mediated improvements in glycemia. We hypothesized that S6K1 may also play a role in regulating glycemic control in response to endurance exercise training. Methods: S6k1-knockout (S6K1KO) and WT mice on a 60 cal%...