Molecular Crystal Forms of Antitubercular Ethionamide with Dicarboxylic Acids: Solid-State Properties and a Combined Structural and Spectroscopic Study

• Main Authors: Simone Bordignon (Author), Paolo Cerreia Vioglio (Author), Elena Amadio (Author), Federica Rossi (Author), Emanuele Priola (Author), Dario Voinovich (Author), Roberto Gobetto (Author), Michele R. Chierotti (Author)
• Format: Book
• Published: MDPI AG, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We report on the preparation, characterization, and bioavailability properties of three new crystal forms of ethionamide, an antitubercular agent used in the treatment of drug-resistant tuberculosis. The new adducts were obtained by combining the active pharmaceutical ingredient with three dicarboxy...