Fabrication of A Folic Acid-Modified Arsenic Trioxide Prodrug Liposome and Assessment of its Anti-Hepatocellular Carcinoma Activity

• Main Authors: Zhu Jing-Jing (Author), Chen Xiao-Jie (Author), Yao Wen-Dong (Author), Wei Ying-Hui (Author), Zheng Hang-Sheng (Author), Zheng Hong-Yue (Author), Zhu Zhi-Hong (Author), Wang Bin-Hui (Author), Li Fan-Zhu (Author)
• Format: Book
• Published: KeAi Communications Co., Ltd., 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To reduce the toxicity and side effects of arsenic trioxide (ATO) and provide a new approach for the treatment of primary liver cancer, a folic acid-modified calcium arsenite liposomal "target-controlled" drug delivery system (FA-LP-CaAs) was fabricated using the reverse microem...