Preparation and Characterization of a Dry Powder Inhaler Composed of PLGA Large Porous Particles Encapsulating Gentamicin Sulfate

• Main Authors: Farideh Shiehzadeh (Author), Mohsen Tafaghodi (Author), Majid Laal-Dehghani (Author), Faezeh Mashhoori (Author), Bibi Sedigheh Fazly Bazzaz (Author), Mohsen Imenshahidi (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Direct delivery of aminoglycosides to the lungs was under extensive evaluations during the last decades. Because of large particle size, low density and porous structure, large porous particles (LPPs) are versatile carriers for this purpose. In this study, poly (lactic-co-glycolic acid) (PL...