Atypical pharmacology of schistosome TRPA1-like ion channels.

• Main Authors: Swarna Bais (Author), Corbett T Berry (Author), Xiaohong Liu (Author), Gordon Ruthel (Author), Bruce D Freedman (Author), Robert M Greenberg (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Parasitic flatworms of the genus Schistosoma cause schistosomiasis, a neglected tropical disease estimated to affect over 200 million people worldwide. Praziquantel is the only antischistosomal currently available for treatment, and there is an urgent need for new therapeutics. Ion channels play key...