LDLR-Mediated Targeting and Productive Uptake of siRNA-Peptide Ligand Conjugates In Vitro and In Vivo

• Main Authors: Baptiste Broc (Author), Karine Varini (Author), Rose Sonnette (Author), Belinda Pecqueux (Author), Florian Benoist (Author), Maxime Masse (Author), Yasmine Mechioukhi (Author), Géraldine Ferracci (Author), Jamal Temsamani (Author), Michel Khrestchatisky (Author), Guillaume Jacquot (Author), Pascaline Lécorché (Author)
• Format: Book
• Published: MDPI AG, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Small RNA molecules such as microRNA and small interfering RNA (siRNA) have become promising therapeutic agents because of their specificity and their potential to modulate gene expression. Any gene of interest can be potentially up- or down-regulated, making RNA-based technology the healthcare brea...